N,2-dimethyl-2-[((2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carbonyl)amino]-N-phenylpropanethioamide

Base Information

• Chemical Name: N,2-dimethyl-2-[((2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carbonyl)amino]-N-phenylpropanethioamide
• CAS No.: 1073615-59-4
• Molecular Formula: C₂₇H₃₄N₄O₂S₂
• Molecular Weight: 510.725
• Mol file: 1073615-59-4.mol

Synonyms:N,2-dimethyl-2-[((2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carbonyl)amino]-N-phenylpropanethioamide

Chemical Property of N,2-dimethyl-2-[((2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carbonyl)amino]-N-phenylpropanethioamide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N,2-dimethyl-2-[((2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carbonyl)amino]-N-phenylpropanethioamide

There total 1 articles about N,2-dimethyl-2-[((2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carbonyl)amino]-N-phenylpropanethioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

(2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carboxylic acid (1073615-56-1) + 2,2-dimethyl-3-(N-methyl-N-phenylamino)-2H-azirine (75755-40-7) → N,2-dimethyl-2-[((2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carbonyl)amino]-N-phenylpropanethioamide (1073615-59-4)

Guidance literature:

(2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carboxylic acid; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; N,N-dimethyl-formamide; at -20 ℃; for 1h;

With hydrogen sulfide; In tetrahydrofuran; N,N-dimethyl-formamide; at -20 ℃; for 3h;

2,2-dimethyl-3-(N-methyl-N-phenylamino)-2H-azirine; In tetrahydrofuran; N,N-dimethyl-formamide; at -10 - 20 ℃;

DOI:10.1002/hlca.200890160

upstream raw materials:

(2S)-1-{2-methyl-2-[(thiobenzoyl)amino]propanoyl}pyrrolidine-2-carboxylic acid

2,2-dimethyl-3-(N-methyl-N-phenylamino)-2H-azirine