N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline

Base Information

Chemical Name:N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline
CAS No.:1364953-08-1
Molecular Formula:C₂₃H₁₅ClF₂N₂O
Molecular Weight:408.835
Hs Code.:

Synonyms:N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline

Suppliers and Price of N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline

There total 2 articles about N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1364952-36-2
N-(2-bromo-1-(2-(4-chlorophenyl)-1H-indol-1-yl)-2,2-difluoroethylidene)-4-methoxyaniline

: 1364953-08-1
N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline

Guidance literature:: With Wilkinson's catalyst; silver carbonate; In 1,4-dioxane; at 120 ℃; for 8h; Inert atmosphere;
DOI:10.1039/c2cc30207a

Reference yield:

: 2-bromo-2,2-difluoro-N-(4-methoxyphenyl)acetimidoyl chloride

: 1211-35-4
2-(4-chlorophenyl)-1H-indole

: 1364953-08-1
N-(3-chloro-5,5-difluoroindolo[2,1-a]isoquinolin-6(5H)-ylidene)-4-methoxyaniline

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran / 1.33 h / 0 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: Wilkinson's catalyst; silver carbonate / 1,4-dioxane / 8 h / 120 °C / Inert atmosphere

With Wilkinson's catalyst; n-butyllithium; silver carbonate; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1039/c2cc30207a