2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

Base Information

• Chemical Name: 2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside
• CAS No.: 873079-92-6
• Molecular Formula: C₃₁H₃₄NO₁₂P
• Molecular Weight: 643.584
• Mol file: 873079-92-6.mol

Synonyms:2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

Chemical Property of 2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

There total 6 articles about 2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C39H40NO14P (873079-91-5) → 2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside (873079-92-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; at 20 ℃; for 12h;

DOI:10.1039/b506348e

Reference yield:

[2-((2S,3S,4S,5S,6R)-3,4,5-Trihydroxy-6-trityloxymethyl-tetrahydro-pyran-2-yloxy)-ethyl]-carbamic acid benzyl ester → 2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside (873079-92-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 0.304 g / pyridine / 12 h

2: 93 percent / aq. HCOOH / tetrahydrofuran / 2 h / 50 °C

3: 94 percent / pyridine / 24 h / 20 °C

4: 92 percent / H₂ / Pd/C / methanol; ethyl acetate / 12 h / 20 °C

With pyridine; formic acid; hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol; ethyl acetate;

DOI:10.1039/b506348e

Reference yield:

N-(benzyloxycarbonylamino)ethyl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside (151567-70-3) → 2-aminoethyl-6-O-dimethylphosphoryl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside (873079-92-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / pyridine / 24 h / 20 °C

2: 92 percent / H₂ / Pd/C / methanol; ethyl acetate / 12 h / 20 °C

With pyridine; hydrogen; palladium on activated charcoal; In methanol; ethyl acetate;

DOI:10.1039/b506348e

upstream raw materials:

C₃₉H₄₀NO₁₄P

N-(benzyloxycarbonylamino)ethyl-2,3,4-tri-O-benzoyl-α-D-mannopyranoside

N-(benzyloxycarbonylamino)ethyl-2,3,4-tri-O-benzoyl-6-O-trityl-α-D-mannopyranoside

C₄₄H₃₉NO₁₂