tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate

Base Information

Chemical Name:tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate
CAS No.:885681-92-5
Molecular Formula:C₁₈H₁₇ClF₃NO₄
Molecular Weight:403.785
Hs Code.:

Synonyms:tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate

Chemical Property:

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Technology Process of tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate

There total 4 articles about tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 873011-54-2
tert-butyl 6-(bromomethyl)-2-[(tert-butoxycarbonyl)oxy]-3-(trifluoromethyl)benzoate

: 41288-96-4
6-chloropyridine-3-ol

: 885681-92-5
tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate

Guidance literature:

Reference yield:

: 873011-52-0
2-hydroxy-6-methyl-3-(trifluoromethyl)benzoic acid

: 885681-92-5
tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate

Guidance literature:: Multi-step reaction with 3 steps

1: tetrahydrofuran; tert-butyl alcohol

2: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane; hexane

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; hexane; tert-butyl alcohol;

Reference yield:

: 873011-53-1
tert-butyl 2-[(tert-butoxycarbonyl)oxy]-6-methyl-3-(trifluoromethyl)benzoate

: 885681-92-5
tert-butyl 6-{[(6-chloro-3-pyridinyl)oxy]methyl}-2-hydroxy-3-(trifluoromethyl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane; hexane

With N-Bromosuccinimide; dibenzoyl peroxide; In tetrachloromethane; hexane;