(4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone

Base Information

Chemical Name:(4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone
CAS No.:187986-23-8
Molecular Formula:C₁₆H₃₀O₄Si
Molecular Weight:314.497
Hs Code.:

Synonyms:(4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone

Suppliers and Price of (4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone

There total 1 articles about (4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ((3R,4S)-4-Dimethoxymethyl-3-isopropyl-6-methyl-cyclohexa-1,5-dienyloxy)-trimethyl-silane

: 187986-23-8
(4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone

Guidance literature:: With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -20 ℃; for 0.333333h;
DOI:10.1021/ja9643432

Reference yield:

: 187986-23-8
(4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone

: 187986-28-3
(1S,2S,6R,8R,10R,11S)-10-(3-chloroperoxybenzoyl)-11-isopropyl-6-methyl-5-methylene-9-oxatricyclo[6.2.1.0^2,6]undecan-7-one

Guidance literature:: Multi-step reaction with 7 steps

1: 79 percent / PTSA*H₂O / CHCl₃ / 6 h / Ambient temperature

2: CuI / tetrahydrofuran / -78 °C

3: Et₃N / tetrahydrofuran / -78 - 20 °C

4: 3.54 g / NaI, m-CPBA / tetrahydrofuran / 0.33 h / Ambient temperature

5: Bu₃SnH, AIBN / benzene / 1 h / Heating

6: 84 percent / TFA / benzene / 0.33 h

7: BF₃*Et₂O / CH₂Cl₂ / 3.5 h

With copper(l) iodide; 2,2'-azobis(isobutyronitrile); boron trifluoride diethyl etherate; tri-n-butyl-tin hydride; toluene-4-sulfonic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; sodium iodide; In tetrahydrofuran; dichloromethane; chloroform; benzene;
DOI:10.1021/ja9643432

Reference yield:

: 187986-23-8
(4R,5S,6R)-4-Dimethoxymethyl-5-isopropyl-2-methyl-6-trimethylsilanyloxy-cyclohex-2-enone

: 2115-91-5,30646-45-8,57760-63-1,62624-23-1,27150-29-4,27298-09-5
dendrobine

Guidance literature:: Multi-step reaction with 14 steps

1: 79 percent / PTSA*H₂O / CHCl₃ / 6 h / Ambient temperature

2: CuI / tetrahydrofuran / -78 °C

3: Et₃N / tetrahydrofuran / -78 - 20 °C

4: 3.54 g / NaI, m-CPBA / tetrahydrofuran / 0.33 h / Ambient temperature

5: Bu₃SnH, AIBN / benzene / 1 h / Heating

6: 84 percent / TFA / benzene / 0.33 h

7: BF₃*Et₂O / CH₂Cl₂ / 3.5 h

8: 57 mg / DBU / CH₂Cl₂ / 1 h / Ambient temperature

9: 1.) BH₃*Me₂S, 2.) H₂O₂, NaOH / 1.) THF, rt, 4.5 h, 2.) THF, H₂O, rt, 12 h

10: CH₂Cl₂; triethylamine / 1.5 h / Ambient temperature

11: 80 percent / NaN₃, 18-crown-6 / dimethylformamide / 1.5 h / 100 °C

12: 94 percent / CrO₃, H₂SO₄ / H₂O; acetone / 1.5 h / Ambient temperature

13: 1.) PPh₃, 2.) NaBH₃CN / 1.) THF, rt, 12 h, 2.) MeOH, AcOH, 12 h

14: 42 percent / H₂O; formic acid / 12 h / 120 °C

With chromium(VI) oxide; sodium hydroxide; copper(l) iodide; sodium azide; 18-crown-6 ether; 2,2'-azobis(isobutyronitrile); dimethylsulfide borane complex; sulfuric acid; boron trifluoride diethyl etherate; dihydrogen peroxide; tri-n-butyl-tin hydride; sodium cyanoborohydride; toluene-4-sulfonic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; trifluoroacetic acid; sodium iodide; In tetrahydrofuran; formic acid; dichloromethane; chloroform; water; triethylamine; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1021/ja9643432