5-(4-Chlorophenyl)-5H-thiazolo[4,3-b]-1,3,4-thiadiazol-2-amine

Base Information

Chemical Name:5-(4-Chlorophenyl)-5H-thiazolo[4,3-b]-1,3,4-thiadiazol-2-amine
CAS No.:137609-26-8
Molecular Formula:C₁₀H₈ClN₃S₂
Molecular Weight:269.779
Hs Code.:
DSSTox Substance ID:DTXSID801178832

Synonyms:DTXSID801178832;5-(4-Chlorophenyl)-5H-thiazolo[4,3-b]-1,3,4-thiadiazol-2-amine;137609-26-8

Suppliers and Price of 5-(4-Chlorophenyl)-5H-thiazolo[4,3-b]-1,3,4-thiadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-Chlorophenyl)-5H-thiazolo[4,3-b]-1,3,4-thiadiazol-2-amine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:268.9848173
Heavy Atom Count:16
Complexity:350

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2N3C(=CS2)SC(=N3)N)Cl

Technology Process of 5-(4-Chlorophenyl)-5H-thiazolo[4,3-b]-1,3,4-thiadiazol-2-amine

There total 2 articles about 5-(4-Chlorophenyl)-5H-thiazolo[4,3-b]-1,3,4-thiadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.1%

: 137609-07-5
[2-(4-Chloro-phenyl)-4-oxo-thiazolidin-3-yl]-thiourea

: 137609-26-8
5-(4-Chloro-phenyl)-thiazolo[4,3-b][1,3,4]thiadiazol-2-ylamine

Guidance literature:: With sulfuric acid;

Reference yield:

: 5706-80-9
4-chlorobenzaldehyde thiosemicarbazone

: 137609-26-8
5-(4-Chloro-phenyl)-thiazolo[4,3-b][1,3,4]thiadiazol-2-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / benzene / 6 h / Heating

2: 80 percent / H₂SO₄ / 0.5 h / 0 °C

With sulfuric acid; In benzene;
DOI:10.1021/jf00039a043