potassium trifluoro(4-fluorobenzoyl)borate

Base Information

• Chemical Name: potassium trifluoro(4-fluorobenzoyl)borate
• CAS No.: 1590389-14-2
• Molecular Formula: C₇H₄BF₄O*K
• Molecular Weight: 230.011
• Mol file: 1590389-14-2.mol

Synonyms:potassium trifluoro(4-fluorobenzoyl)borate

Chemical Property of potassium trifluoro(4-fluorobenzoyl)borate

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

Potassium 4-fluorobenzoyltrifluoroborate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: Potassium Acyltrifluroborates (KAT′s) are bench, air, and moisture stable reagents for rapid, chemoselective amide bond formations with hydroxylamines. These amide bond forming reactions proceed under aqueous conditions, without the need for coupling reagents or protecting groups. This product was introduced in collaboration with the Bode Research Group.

Technology Process of potassium trifluoro(4-fluorobenzoyl)borate

There total 7 articles about potassium trifluoro(4-fluorobenzoyl)borate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

C12H11BFNO5 → potassium trifluoro(4-fluorobenzoyl)borate (1590389-14-2)

Guidance literature:

With potassium hydrogenfluoride; In tetrahydrofuran; water; at 23 ℃; for 12h;

DOI:10.1039/c4sc00971a

Reference yield: 93.0%

potassium trifluoro[(4-fluorophenyl)(hydroxy)methyl]borate → potassium trifluoro(4-fluorobenzoyl)borate (1590389-14-2)

Guidance literature:

With acetic anhydride; In dimethyl sulfoxide; at 20 ℃; for 2h; Reagent/catalyst; Solvent; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.201901748

Reference yield:

1-(methoxy(4-fluorophenyl)methyl)-1H-benzotriazole (1590361-26-4) → potassium trifluoro(4-fluorobenzoyl)borate (1590389-14-2)

Guidance literature:

1-(methoxy(4-fluorophenyl)methyl)-1H-benzotriazole; With n-butyllithium; In tetrahydrofuran; hexane; at -110 - 20 ℃; for 0.133333h; Inert atmosphere;

With Trimethyl borate; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

With potassium hydrogen difluoride; In tetrahydrofuran; for 12h; Inert atmosphere;

DOI:10.1021/ja5018442

upstream raw materials:

1-(methoxy(4-fluorophenyl)methyl)-1H-benzotriazole

4-fluorobenzaldehyde

water

potassium fluoride

Downstream raw materials:

N-(2-phenylethyl)-4-fluorobenzamide

4-fluoro-N-(3-phenylpropyl)-benzamide

(E)-2-((4-(dimethylamino)phenyl)diazenyl)-N-(3-(4-(phenethylcarbamoyl)phenoxy)propyl)benzamide

C₂₅H₃₁N₃O₃S