5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine

Base Information

• Chemical Name: 5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine
• CAS No.: 332109-24-7
• Molecular Formula: C₁₇H₁₄N₂O₂S
• Molecular Weight: 310.376
• Mol file: 332109-24-7.mol

Synonyms:5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine

Chemical Property of 5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine

There total 5 articles about 5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

5-((Z)-4-hydroxybenzylidene)-2-thioxo-4-thiazolidinone (81154-14-5) + benzylamine (100-46-9) → 5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine (332109-24-7)

Guidance literature:

In ethanol; for 5h; Heating;

Reference yield: 31.0%

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) + 2-(benzylimino)thiazolidin-4-one (17385-69-2) → 5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine (332109-24-7)

Guidance literature:

With sodium acetate; acetic acid; for 72h; Reflux; Inert atmosphere;

DOI:10.1016/j.ejmech.2016.04.075

Reference yield:

N-benzylthiourea (621-83-0) → 5-(4-hydroxyphenylmethylene)-2-benzylimino-4-oxothiazolidine (332109-24-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate / ethanol / 6 h / Reflux; Inert atmosphere

2: sodium acetate; acetic acid / 72 h / Reflux; Inert atmosphere

With sodium acetate; acetic acid; In ethanol;

DOI:10.1016/j.ejmech.2016.04.075

upstream raw materials:

5-((Z)-4-hydroxybenzylidene)-2-thioxo-4-thiazolidinone

benzylamine

N-benzylthiourea

4-hydroxy-benzaldehyde