2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)-

Base Information

Chemical Name:2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)-
CAS No.:1456807-80-9
Molecular Formula:C₁₆H₂₀N₂O₄
Molecular Weight:304.346
Hs Code.:
Mol file:1456807-80-9.mol

Synonyms:7-hydroxy-5-methoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-benzopyran-2-one

Suppliers and Price of 2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 7 raw suppliers

Chemical Property of 2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)-

Chemical Property:

Boiling Point:528.3±50.0 °C(Predicted)
PKA:8.05±0.20(Predicted)
Density:1.280±0.06 g/cm3(Predicted)

Purity/Quality:: 99.3% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)-

There total 10 articles about 2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1456807-86-5
C₂₃H₂₇N₂O₄⁽¹⁺⁾

: 1456807-80-9
7-hydroxy-5-methoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-benzopyran-2-one

Guidance literature:: With palladium on activated charcoal; ammonium formate; In methanol; for 0.666667h; Reflux;
DOI:10.1016/j.ejmech.2013.04.015

Reference yield:

: 1209261-56-2
5,7-dihydroxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-chromen-2-one

: 77-78-1
dimethyl sulfate

: 1209261-73-3
5-hydroxy-7-methoxy-4-methyl-3 (4-methylpiperazin-1-yl)-2H-benzopyran-2-one

: 1456807-80-9
7-hydroxy-5-methoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-benzopyran-2-one

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃;
DOI:10.1016/j.ejmech.2013.04.015

Reference yield:

: 1456807-82-1
C₂₉H₃₀N₂O₈S₂

: 1456807-80-9
7-hydroxy-5-methoxy-4-methyl-3-(4-methylpiperazin-1-yl)-2H-benzopyran-2-one

Guidance literature:: Multi-step reaction with 5 steps

1: potassium carbonate / acetone / 20 °C

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 °C

3: potassium carbonate / 2.08 h / 20 °C / Reflux

4: tetrabutyl ammonium fluoride / tetrahydrofuran / 20 °C

5: palladium on activated charcoal; ammonium formate / methanol / 0.67 h / Reflux

With palladium on activated charcoal; tetrabutyl ammonium fluoride; ammonium formate; potassium carbonate; In tetrahydrofuran; methanol; acetone;
DOI:10.1016/j.ejmech.2013.04.015