ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate

Base Information

Chemical Name:ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate
CAS No.:503603-89-2
Molecular Formula:C₁₈H₂₅NO₂
Molecular Weight:287.402
Hs Code.:

Synonyms:ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate

Suppliers and Price of ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate

There total 8 articles about ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 181941-65-1
ethyl 1-{(3S)-1-[(S)-1-phenylethyl]-5-thioxopyrrolidin-3-yl}cyclopropanecarboxylate

: 503603-89-2
ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate

Guidance literature:: With Raney Ni W-6; In ethanol; for 6h; Heating;
DOI:10.1021/jm020328y

Reference yield:

: 2627-86-3
(S)-1-phenyl-ethylamine

: 503603-89-2
ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 13.1 g / NaHCO₃ / ethanol / 4 h / Heating

2: 74 percent / H₂ / PtO₂ / methanol / 18 h / 20 °C

3: 98 percent / Lawesson's reagent / benzene / 3 h / Heating

4: 91 percent / Raney Ni W-6 / ethanol / 6 h / Heating

With Lawessons reagent; Raney Ni W-6; hydrogen; sodium hydrogencarbonate; platinum(IV) oxide; In methanol; ethanol; benzene;
DOI:10.1021/jm020328y

Reference yield:

: 181941-62-8
ethyl (E)-3-(1-ethoxycarbonylcyclopropan-1-yl)-2-butenoate

: 503603-89-2
ethyl 1-{(3S)-1-[(S)-1-phenylethyl]pyrrolidin-3-yl}cyclopropanecarboxylate

Guidance literature:: Multi-step reaction with 5 steps

1: NBS; AIBN / CCl₄ / 5 h / Heating

2: 13.1 g / NaHCO₃ / ethanol / 4 h / Heating

3: 74 percent / H₂ / PtO₂ / methanol / 18 h / 20 °C

4: 98 percent / Lawesson's reagent / benzene / 3 h / Heating

5: 91 percent / Raney Ni W-6 / ethanol / 6 h / Heating

With Lawessons reagent; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); Raney Ni W-6; hydrogen; sodium hydrogencarbonate; platinum(IV) oxide; In methanol; tetrachloromethane; ethanol; benzene;
DOI:10.1021/jm020328y