Pyrazino[2,1-a]isoindole, 1,2,3,4,6,10b-hexahydro-1-methyl- (9CI)

Base Information

Chemical Name:Pyrazino[2,1-a]isoindole, 1,2,3,4,6,10b-hexahydro-1-methyl- (9CI)
CAS No.:79017-19-9
Molecular Formula:C₁₂H₁₆N₂
Molecular Weight:188.272
Hs Code.:
Mol file:79017-19-9.mol

Synonyms:Pyrazino[2,1-a]isoindole, 1,2,3,4,6,10b-hexahydro-1-methyl- (9CI);1-METHYL-1,2,3,4,6,10B-HEXAHYDROPYRAZINO[2,1-A]ISOINDOLE

Suppliers and Price of Pyrazino[2,1-a]isoindole, 1,2,3,4,6,10b-hexahydro-1-methyl- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Pyrazino[2,1-a]isoindole, 1,2,3,4,6,10b-hexahydro-1-methyl- (9CI)

Chemical Property:

PSA：15.27000
LogP:1.80170

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Pyrazino[2,1-a]isoindole, 1,2,3,4,6,10b-hexahydro-1-methyl- (9CI)

There total 8 articles about Pyrazino[2,1-a]isoindole, 1,2,3,4,6,10b-hexahydro-1-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 79017-08-6,97049-60-0,97049-75-7
3-(1-nitroethyl)-1(3H)-isobenzofuranone

: 79017-19-9,79017-45-1,79017-20-2
1α-methyl-1,2,3,4,6,10b-hexahydropyrazino<2,1-a>isoindole

Guidance literature:: Multi-step reaction with 5 steps

1: 78 percent / K₂CO₃ / acetone / 18 h / Ambient temperature

2: sodium acetate / acetonitrile / 4 h

3: 0.880 g / H₂ / 10percent Pd/C / acetic acid; H₂O / 18 h / 2585.7 Torr / Ambient temperature

4: H₂ / 10percent Pd/C / methanol; aq. HCl / 48 h / 760 Torr / Ambient temperature

5: 1 M solution of diborane / tetrahydrofuran / 18 h / Heating

With hydrogen; sodium acetate; potassium carbonate; diborane; palladium on activated charcoal; In tetrahydrofuran; hydrogenchloride; methanol; water; acetic acid; acetone; acetonitrile;
DOI:10.1139/v85-061

Reference yield:

: 97049-77-9
2-<(2-methyl-2-nitro)ethylene>benzoic acid methyl ester

: 79017-19-9,79017-45-1,79017-20-2
1α-methyl-1,2,3,4,6,10b-hexahydropyrazino<2,1-a>isoindole

Guidance literature:: Multi-step reaction with 4 steps

1: sodium acetate / acetonitrile / 4 h

2: 0.880 g / H₂ / 10percent Pd/C / acetic acid; H₂O / 18 h / 2585.7 Torr / Ambient temperature

3: H₂ / 10percent Pd/C / methanol; aq. HCl / 48 h / 760 Torr / Ambient temperature

4: 1 M solution of diborane / tetrahydrofuran / 18 h / Heating

With hydrogen; sodium acetate; diborane; palladium on activated charcoal; In tetrahydrofuran; hydrogenchloride; methanol; water; acetic acid; acetonitrile;
DOI:10.1139/v85-061

Reference yield:

: 79017-11-1,79017-42-8
2,3-dihydro-2-(2,2-diethoxyethyl)-3-(1-nitroethyl)-isoindol-1-one

: 79017-19-9,79017-45-1,79017-20-2
1α-methyl-1,2,3,4,6,10b-hexahydropyrazino<2,1-a>isoindole

Guidance literature:: Multi-step reaction with 3 steps

1: 0.880 g / H₂ / 10percent Pd/C / acetic acid; H₂O / 18 h / 2585.7 Torr / Ambient temperature

2: H₂ / 10percent Pd/C / methanol; aq. HCl / 48 h / 760 Torr / Ambient temperature

3: 1 M solution of diborane / tetrahydrofuran / 18 h / Heating

With hydrogen; diborane; palladium on activated charcoal; In tetrahydrofuran; hydrogenchloride; methanol; water; acetic acid;
DOI:10.1139/v85-061