4-Tert-Butyl-N-(5-Hydroxy-4-Methyl-2-(2-Oxo-3-Phenylindolin-3-Yl)Phenyl)Benzenesulfonamide

Base Information

Chemical Name:4-Tert-Butyl-N-(5-Hydroxy-4-Methyl-2-(2-Oxo-3-Phenylindolin-3-Yl)Phenyl)Benzenesulfonamide
CAS No.:783324-18-5
Molecular Formula:C₃₁H₃₀N₂O₄S
Molecular Weight:526.656
Hs Code.:
DSSTox Substance ID:DTXSID90439481
ChEMBL ID:CHEMBL366132
Mol file:783324-18-5.mol

Synonyms:783324-18-5;4-Tert-Butyl-N-(5-Hydroxy-4-Methyl-2-(2-Oxo-3-Phenylindolin-3-Yl)Phenyl)Benzenesulfonamide;4-(tert-Butyl)-N-(5-hydroxy-4-methyl-2-(2-oxo-3-phenylindolin-3-yl)phenyl)benzenesulfonamide;4-tert-butyl-N-[5-hydroxy-4-methyl-2-(2-oxo-3-phenyl-1H-indol-3-yl)phenyl]benzenesulfonamide;SCHEMBL209645;CHEMBL366132;DTXSID90439481;AZFAPIZFJPRMSM-UHFFFAOYSA-N;FT-0736472;A19175;4-tert-butyl-N-[5-hydroxy-4-methyl-2-(2-oxo-3-phenyl-2,3 -dihydro-1H-indol-3-yl)-phenyl]-benzenesulfonamide;4-tert-Butyl-N-[5-hydroxy-4-methyl-2-(2-oxo-3-phenyl-2,3-dihydro-1H-indol-3-yl)-phenyl]-benzenesulfonamide;4-tert-butyl-N-[5-hydroxy-4-methyl-2-(2-oxo-3-phenyl-2,3-dihydro-1H-indol-3-yl)phenyl]benzene-1-sulfonamide

Suppliers and Price of 4-Tert-Butyl-N-(5-Hydroxy-4-Methyl-2-(2-Oxo-3-Phenylindolin-3-Yl)Phenyl)Benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-Tert-Butyl-N-(5-Hydroxy-4-Methyl-2-(2-Oxo-3-Phenylindolin-3-Yl)Phenyl)Benzenesulfonamide

Chemical Property:

PSA：107.37000
LogP:7.32430
XLogP3:6.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:526.19262862
Heavy Atom Count:38
Complexity:942

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1O)NS(=O)(=O)C2=CC=C(C=C2)C(C)(C)C)C3(C4=CC=CC=C4NC3=O)C5=CC=CC=C5

Technology Process of 4-Tert-Butyl-N-(5-Hydroxy-4-Methyl-2-(2-Oxo-3-Phenylindolin-3-Yl)Phenyl)Benzenesulfonamide

There total 3 articles about 4-Tert-Butyl-N-(5-Hydroxy-4-Methyl-2-(2-Oxo-3-Phenylindolin-3-Yl)Phenyl)Benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 139018-14-7,1848-24-4
3-hydroxy-3-phenyl-1,3-dihydro-indol-2-one

: 723290-46-8
4-tert-butyl-N-(3-hydroxy-4-methyl-phenyl)-benzenesulfonamide

: 783324-18-5
4-tert-butyl-N-[5-hydroxy-4-methyl-2-(2-oxo-3-phenyl-2,3-dihydro-1H-indol-3-yl)-phenyl]-benzenesulfonamide

Guidance literature:: With toluene-4-sulfonic acid; In 1,2-dichloro-ethane; at 95 ℃; for 3h;
DOI:10.1021/jm0496234

Reference yield:

: 15084-51-2
4-tert-butylbenzenesulfonyl chloride

: 783324-18-5
4-tert-butyl-N-[5-hydroxy-4-methyl-2-(2-oxo-3-phenyl-2,3-dihydro-1H-indol-3-yl)-phenyl]-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 20 °C

2: 86 percent / p-toluenesulfonic acid / 1,2-dichloro-ethane / 3 h / 95 °C

With pyridine; toluene-4-sulfonic acid; In 1,2-dichloro-ethane;
DOI:10.1021/jm0496234

Reference yield:

: 2835-95-2
amino-4 hydroxy-2 toluene

: 783324-18-5
4-tert-butyl-N-[5-hydroxy-4-methyl-2-(2-oxo-3-phenyl-2,3-dihydro-1H-indol-3-yl)-phenyl]-benzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 20 °C

2: 86 percent / p-toluenesulfonic acid / 1,2-dichloro-ethane / 3 h / 95 °C

With pyridine; toluene-4-sulfonic acid; In 1,2-dichloro-ethane;
DOI:10.1021/jm0496234