(1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt

Base Information

Chemical Name:(1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt
CAS No.:1613473-31-6
Molecular Formula:C₂HF₃O₂*C₁₀H₁₃N
Molecular Weight:261.244
Hs Code.:

Synonyms:(1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt

Suppliers and Price of (1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt

There total 4 articles about (1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1613475-50-5
tert-butyl-N-[(1S,2R)-1-methyl-2-phenyl-cyclopropyl]carbamate

: 76-05-1
trifluoroacetic acid

: 1613473-31-6
(1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt

Guidance literature:: In dichloromethane; at 20 ℃;
DOI:10.1016/j.ejmech.2014.08.068

Reference yield:

: 10152-79-1,10258-87-4,10606-69-6,10606-82-3,13005-22-6,133124-29-5
(1S,2R)-1-methyl-2-phenyl-cyclopropanecarboxylic acid

: 1613473-31-6
(1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt

Guidance literature:: Multi-step reaction with 2 steps

1: diphenyl phosphoryl azide; triethylamine / 18 h / 90 °C

2: dichloromethane / 20 °C

With diphenyl phosphoryl azide; triethylamine; In dichloromethane; 1: |Curtius Rearrangement;
DOI:10.1016/j.ejmech.2014.08.068

Reference yield:

: ethyl (1S,2R)-1-methyl-2-phenylcyclopropane-1-carboxylate

: 1613473-31-6
(1S,2R)-1-methyl-2-phenylcyclopropanamine 2,2,2-trifluoroacetic acid salt

Guidance literature:: Multi-step reaction with 3 steps

1: water; lithium hydroxide / ethanol; tetrahydrofuran / 1 h / 0 - 115 °C / Microwave irradiation

2: diphenyl phosphoryl azide; triethylamine / 18 h / 90 °C

3: dichloromethane / 20 °C

With diphenyl phosphoryl azide; water; triethylamine; lithium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; 2: |Curtius Rearrangement;
DOI:10.1016/j.ejmech.2014.08.068