(2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine

Base Information

Chemical Name:(2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine
CAS No.:1037306-51-6
Molecular Formula:C₂₅H₃₃NO₅
Molecular Weight:427.541
Hs Code.:

Synonyms:(2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine

Suppliers and Price of (2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine

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Technology Process of (2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine

There total 1 articles about (2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1037306-50-5
(2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-[(tert-butyldiphenylsilyloxy)methyl]-5-methylpyrrolidine

: 1037306-51-6
(2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 6h;
DOI:10.1055/s-2008-1072566

Reference yield: 39.0%

: 1037306-51-6
(2R,3S,4R,5R)-3,4-bis(benzyloxy)-1-(tert-butoxycarbonyl)-2-(hydroxymethyl)-5-methylpyrrolidine

: 637771-89-2,734531-46-5
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-methylpyrrolidine-3,4-diol

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 48h; under 3000.3 Torr;
DOI:10.1055/s-2008-1072566