2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid cyclohexylamide

Base Information

Chemical Name:2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid cyclohexylamide
CAS No.:1040741-71-6
Molecular Formula:C₂₃H₃₇IN₄O
Molecular Weight:512.477
Hs Code.:

Synonyms:2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid cyclohexylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid cyclohexylamide

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Technology Process of 2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid cyclohexylamide

There total 1 articles about 2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid cyclohexylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 931-53-3
Cyclohexyl isocyanide

: 69696-38-4
5-iodo-2-isopropyl-6-methyl-pyrimidin-4-ol

: 107-11-9,30551-89-4
1-amino-2-propene

: 590-86-3
isovaleraldehyde

: 1040741-71-6
2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid cyclohexylamide

Guidance literature:: In methanol; at 60 ℃; for 72h; Inert atmosphere;
DOI:10.1021/ol801217a

Reference yield: 69.0%

: 1040741-71-6
2-[allyl-(5-iodo-2-isopropyl-6-methyl-pyrimidin-4-yl)-amino]-4-methylpentanoic acid cyclohexylamide

: 1040741-81-8
N-cyclohexyl-2-(2-isopropyl-4,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-4-methylpentanamide

Guidance literature:: With palladium diacetate; triethylamine; triphenylphosphine; In methanol; at 60 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol801217a