N-benzo[b]thieno-2-yl-L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex

Base Information

• Chemical Name: N-benzo[b]thieno-2-yl-L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex
• CAS No.: 1161426-67-0
• Molecular Formula: C₃₄H₄₅N₃O₄S
• Molecular Weight: 591.815

Synonyms:N-benzo[b]thieno-2-yl-L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex

Chemical Property of N-benzo[b]thieno-2-yl-L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex

Chemical Property:

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Technology Process of N-benzo[b]thieno-2-yl-L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex

There total 1 articles about N-benzo[b]thieno-2-yl-L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

benzothiophene-2-carboxylic acid chloride (39827-11-7) + L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex, trifluoroacetic salt (1194605-42-9) → N-benzo[b]thieno-2-yl-L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex (1161426-67-0)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jm900628z

upstream raw materials:

benzothiophene-2-carboxylic acid chloride

L-Glu[NH-2-(1-benzylpiperidin-4-yl)ethyl]-O-nHex, trifluoroacetic salt

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