methyl (1R^*,2S^*,3S^*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate

Base Information

• Chemical Name: methyl (1R^*,2S^*,3S^*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate
• CAS No.: 80090-59-1
• Molecular Formula: C₂₂H₃₈O₆
• Molecular Weight: 398.54

Synonyms:methyl (1R^*,2S^*,3S^*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate

Chemical Property of methyl (1R^*,2S^*,3S^*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (1R^*,2S^*,3S^*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate

There total 22 articles about methyl (1R^*,2S^*,3S^*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl (1R*,2S*,3S*)-2-butyl-1-(3-ethoxycarbonyl-2-propenyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate (80090-58-0) → methyl (1R*,2S*,3S*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate (80090-59-1)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol;

DOI:10.1248/cpb.30.2840

Reference yield: 98.0%

(1R,2S,3S)-2-Butyl-1-((E)-3-ethoxycarbonyl-allyl)-3-(tetrahydro-furan-2-yloxy)-cyclohexanecarboxylic acid methyl ester (80090-58-0) → (1R,2S,3S)-2-Butyl-1-(3-ethoxycarbonyl-propyl)-3-(tetrahydro-furan-2-yloxy)-cyclohexanecarboxylic acid methyl ester (80090-59-1)

Guidance literature:

With hydrogen; platinum(IV) oxide;

DOI:10.1246/cl.1981.1409

Reference yield:

methyl (1R*,2S*,3S*)-2-butyl-3-hydroxy-1-cyclohexanecarboxylate (80090-54-6,84277-34-9,88823-65-8,88823-68-1,90411-07-7) → methyl (1R*,2S*,3S*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate (80090-59-1)

Guidance literature:

Multi-step reaction with 6 steps

1: 95 percent / pyridinium p-toluenesulfonate / CHCl₃ / 2 h / 0 °C

3: 92 percent / pyridinium p-toluenesulfonate / CHCl₃ / 1 h / 0 °C

4: 1.) N-methylmorpholine N-oxide, osmium tetroxide, 2.) sodium periodate / 1.) THF/water, RT, 15 min, 2.) THF/water, RT, 3.5 h

5: 1.) NaH / diethyl ether / 0 °C / 1.) 0 deg C, 1 h, 2.) 0 deg C, 15 min

6: 98 percent / H₂ / PtO_2.2H₂O / ethanol

With sodium periodate; osmium(VIII) oxide; hydrogen; pyridinium p-toluenesulfonate; sodium hydride; 4-methylmorpholine N-oxide; platinum(IV) oxide; In diethyl ether; ethanol; chloroform;

DOI:10.1248/cpb.30.2840

upstream raw materials:

(1R,2S,3S)-2-Butyl-1-((E)-3-ethoxycarbonyl-allyl)-3-(tetrahydro-furan-2-yloxy)-cyclohexanecarboxylic acid methyl ester

1-<3-(tert-butyldimethylsiloxy)cyclohex-1-enyl>ethanone

1-[(1S,2R,3R)-2-Butyl-3-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl]-ethanone

(1R,2S,3S)-2-Butyl-3-hydroxy-cyclohexanecarboxylic acid methyl ester

Downstream raw materials:

(6R^*,7S^*,8S^*)-7-butyl-8-(4-methylphenylsulfonyloxy)-1-azaspiro<5.5>undecan-2-one

Toluene-4-sulfonic acid (6R,7S,8S)-7-butyl-2-oxo-1-aza-spiro[5.5]undec-8-yl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 80090-59-1 methyl (1R^*,2S^*,3S^*)-2-butyl-1-(3-ethoxycarbonylpropyl)-3-(2-tetrahydrofuranyloxy)-1-cyclohexanecarboxylate

Send

Send

Metric Ton KG G Pound L ML

Send

Send