(2S,3S)-methyl 2-hydroxy-5-(1-methyl-1H-imidazol-2-yl)-5-oxo-2-phenyl-3-p-tolylpentanoate

Base Information

Chemical Name:(2S,3S)-methyl 2-hydroxy-5-(1-methyl-1H-imidazol-2-yl)-5-oxo-2-phenyl-3-p-tolylpentanoate
CAS No.:1227009-01-9
Molecular Formula:C₂₃H₂₄N₂O₄
Molecular Weight:392.455
Hs Code.:

Synonyms:(2S,3S)-methyl 2-hydroxy-5-(1-methyl-1H-imidazol-2-yl)-5-oxo-2-phenyl-3-p-tolylpentanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,3S)-methyl 2-hydroxy-5-(1-methyl-1H-imidazol-2-yl)-5-oxo-2-phenyl-3-p-tolylpentanoate

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Technology Process of (2S,3S)-methyl 2-hydroxy-5-(1-methyl-1H-imidazol-2-yl)-5-oxo-2-phenyl-3-p-tolylpentanoate

There total 1 articles about (2S,3S)-methyl 2-hydroxy-5-(1-methyl-1H-imidazol-2-yl)-5-oxo-2-phenyl-3-p-tolylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 22979-35-7
Methyl phenyldiazoacetate

: 118416-05-0
2-<3-(4-methylphenyl)acryloyl>-1-methyl-1H-imidazole

: 1227009-01-9
(2S,3S)-methyl 2-hydroxy-5-(1-methyl-1H-imidazol-2-yl)-5-oxo-2-phenyl-3-p-tolylpentanoate

Guidance literature:: With dirhodium tetraacetate; (S)-tBu-box-Zn(OTf)2; water; toluene-4-sulfonic acid; In dichloromethane; at -8 ℃; optical yield given as %ee; enantioselective reaction;
DOI:10.1002/anie.200904905