5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole

Base Information

• Chemical Name: 5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole
• CAS No.: 109105-62-6
• Molecular Formula: C₂₁H₂₃ClN₂O₄S
• Molecular Weight: 434.944

Synonyms:5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole

Chemical Property of 5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole

There total 3 articles about 5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropyl>-4-hydroxy-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole (109105-61-5) → 5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole (109105-62-6)

Guidance literature:

With phosphoric acid; In benzene; for 0.333333h; Heating;

DOI:10.3987/R-1986-11-3149

Reference yield:

N,N-Dimethylacetoacetamid (2044-64-6) → 5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole (109105-62-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH, BuLi / 1.) THF, hexane, -78 deg C, 2.) THF, hexane, RT, 3.5 h

2: 90 percent / phosphoric acid / benzene / 0.33 h / Heating

With n-butyllithium; phosphoric acid; sodium hydride; In benzene;

DOI:10.3987/R-1986-11-3149

Reference yield:

5-chloro-4-oxo-N-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole (95969-07-6) → 5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole (109105-62-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH, BuLi / 1.) THF, hexane, -78 deg C, 2.) THF, hexane, RT, 3.5 h

2: 90 percent / phosphoric acid / benzene / 0.33 h / Heating

With n-butyllithium; phosphoric acid; sodium hydride; In benzene;

DOI:10.3987/R-1986-11-3149

upstream raw materials:

5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropyl>-4-hydroxy-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole

N,N-Dimethylacetoacetamid

5-chloro-4-oxo-N-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 109105-62-6 5-chloro-4-<3-(N,N-dimethylaminocarbonyl)-2-oxopropylidene>-1-(p-toluenesulfonyl)-4,5,6,7-tetrahydroindole

Send

Send

Metric Ton KG G Pound L ML

Send

Send