Technology Process of (S)(-)-ethyl N-(cyclohexene-1-carbonyl)prolinate
There total 4 articles about (S)(-)-ethyl N-(cyclohexene-1-carbonyl)prolinate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
diethyl cyanophosphonate; triethylamine;
In
N,N-dimethyl-formamide;
for 49h;
1) 0 deg C, 1 h; 2) room temp., 48 h;
DOI:10.1016/S0040-4020(01)92348-8
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Jones reagent / acetone / 2 h / Ambient temperature
2: 98 percent / diethyl phosphorocyanidate, Et3N / dimethylformamide / 49 h / 1) 0 deg C, 1 h; 2) room temp., 48 h
With
jones reagent; diethyl cyanophosphonate; triethylamine;
In
N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)92348-8
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 50 percent / 30percent H2O2, 85percent HCOOH / H2O / 25 h / 1) 50 deg C, 1 h; 2) room temp., 24 h
2: 35 percent / HNO3, NaIO4 / H2O / 44 h / Ambient temperature; pH = 4
3: Jones reagent / acetone / 2 h / Ambient temperature
4: 98 percent / diethyl phosphorocyanidate, Et3N / dimethylformamide / 49 h / 1) 0 deg C, 1 h; 2) room temp., 48 h
With
sodium periodate; formic acid; jones reagent; diethyl cyanophosphonate; dihydrogen peroxide; nitric acid; triethylamine;
In
water; N,N-dimethyl-formamide; acetone;
DOI:10.1016/S0040-4020(01)92348-8
