Technology Process of (R)-1,2-Heptanediol
There total 35 articles about (R)-1,2-Heptanediol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
AD-mix-β;
In
water; tert-butyl alcohol;
at 0 ℃;
for 120h;
DOI:10.1021/ol500050p
- Guidance literature:
-
With
[bis(2-methylallyl)cycloocta-1,5-diene]ruthenium(II); 3-(2,5-(2R,5R)-dimethylphospholanyl-1)-4-dio-tolylphosphino-2,5-dimethylthiophene; hydrogen bromide; hydrogen;
In
methanol;
at 60 ℃;
under 37503.8 Torr;
optical yield given as %ee;
enantioselective reaction;
Inert atmosphere;
DOI:10.1002/anie.200902835
- Guidance literature:
-
With
osmium(VIII) oxide; (1R,2R)-bis(dimethylamino)cyclohexane;
In
dichloromethane;
for 2h;
Mechanism;
Ambient temperature;
other olefins investigated; enantioselective reaction;
DOI:10.1016/S0040-4039(00)84881-9
