2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

Base Information

Chemical Name:2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione
CAS No.:81321-85-9
Molecular Formula:C₂₇H₂₄FN₃OS
Molecular Weight:457.571
Hs Code.:

Synonyms:2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

Suppliers and Price of 2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

There total 4 articles about 2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 31603-77-7
4-biphenylacetonitrile

: 81321-85-9
2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) diisobutylaluminum hydride 2.) sulphuric acid / 1.) toluene, -5 deg C, 1 h; 2.) ethanol, water

2: triethylamine / CHCl₃ / 1.) 3h, reflux, 2.) room temp.

3: HCl / dioxane; H₂O / 1 h / 100 °C

4: sulphur / 3 h / Heating

With hydrogenchloride; sulfuric acid; diisobutylaluminium hydride; sulfur; triethylamine; In 1,4-dioxane; chloroform; water;

Reference yield:

: 81321-35-9
(E)-N-[2-(4-Biphenyl)ethenyl]morpholine

: 81321-85-9
2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / CHCl₃ / 1.) 3h, reflux, 2.) room temp.

2: HCl / dioxane; H₂O / 1 h / 100 °C

3: sulphur / 3 h / Heating

With hydrogenchloride; sulfur; triethylamine; In 1,4-dioxane; chloroform; water;

Reference yield:

: 1-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-5-morpholin-4-yl-4,5-dihydro-1H-pyrazol-3-yl]-ethanone

: 81321-85-9
2-[4-Biphenyl-4-yl-1-(4-fluoro-phenyl)-1H-pyrazol-3-yl]-1-morpholin-4-yl-ethanethione

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / dioxane; H₂O / 1 h / 100 °C

2: sulphur / 3 h / Heating

With hydrogenchloride; sulfur; In 1,4-dioxane; water;