2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole

Base Information

Chemical Name:2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole
CAS No.:1428958-95-5
Molecular Formula:C₁₈H₁₂Cl₂N₄O₂S
Molecular Weight:419.291
Hs Code.:

Synonyms:2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole

Suppliers and Price of 2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole

There total 3 articles about 2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67370-32-5
2-(3,4-dichlorophenyl)-1H-benzo[d]imidazole

: 1428958-95-5
2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole

Guidance literature:: 2-(3,4-dichlorophenyl)-1H-benzo[d]imidazole; 4-halo-2-(methylthio)pyrimidine; With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; BINAP; sodium t-butanolate; In toluene; at 130 ℃; for 3h; Inert atmosphere;

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 8h;
DOI:10.1016/j.bmc.2013.02.021

Reference yield:

: 6287-38-3
3,4-dichlorobenzaldehyde

: 1428958-95-5
2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: dihydrogen peroxide / methanol / 50 °C

2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; BINAP; sodium t-butanolate / toluene / 3 h / 130 °C / Inert atmosphere

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; BINAP; dihydrogen peroxide; sodium t-butanolate; In methanol; toluene;
DOI:10.1016/j.bmc.2013.02.021

Reference yield:

: 95-54-5
1,2-diamino-benzene

: 1428958-95-5
2-(3,4-dichloro-phenyl)-1-(2-methanesulfonyl-pyrimidin-4-yl)-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: dihydrogen peroxide / methanol / 50 °C

2.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; BINAP; sodium t-butanolate / toluene / 3 h / 130 °C / Inert atmosphere

2.2: 8 h / 20 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; BINAP; dihydrogen peroxide; sodium t-butanolate; In methanol; toluene;
DOI:10.1016/j.bmc.2013.02.021