3-[4-(Trifluoromethyl)phenoxy]aniline

Base Information

Chemical Name:3-[4-(Trifluoromethyl)phenoxy]aniline
CAS No.:78748-23-9
Molecular Formula:C₁₃H₁₀F₃NO
Molecular Weight:253.224
Hs Code.:
DSSTox Substance ID:DTXSID10516102
Wikidata:Q82377356
Mol file:78748-23-9.mol

Synonyms:78748-23-9;3-[4-(trifluoromethyl)phenoxy]aniline;Benzenamine,3-[4-(trifluoromethyl)phenoxy]-;3-(4-TRIFLUOROMETHYL-PHENOXY)-PHENYLAMINE;3-(4-trifluoromethylphenoxy)aniline;SCHEMBL4703990;DTXSID10516102;3-(4 trifluoromethylphenoxy)aniline;MFCD06656970;AKOS011943485;3- (4-TRIFLUOROMETHYLPHENOXY)ANILINE;D87604;A1-47897

Suppliers and Price of 3-[4-(Trifluoromethyl)phenoxy]aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
3-(4-trifluoromethyl-phenoxy)-phenylamine 95
10g
$ 2475.00

Labseeker
3-(4-trifluoromethyl-phenoxy)-phenylamine 95
1g
$ 1283.00

American Custom Chemicals Corporation
3-(4-TRIFLUOROMETHYL-PHENOXY)-PHENYLAMINE 95.00%
5MG
$ 504.88

Total 6 raw suppliers

Chemical Property of 3-[4-(Trifluoromethyl)phenoxy]aniline

Chemical Property:

PSA：35.25000
LogP:4.66110
XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:253.07144843
Heavy Atom Count:18
Complexity:262

Purity/Quality:

99%+ ^*data from raw suppliers

3-(4-trifluoromethyl-phenoxy)-phenylamine 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)OC2=CC=C(C=C2)C(F)(F)F)N

Technology Process of 3-[4-(Trifluoromethyl)phenoxy]aniline

There total 3 articles about 3-[4-(Trifluoromethyl)phenoxy]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 402-44-8
4-Fluorobenzotrifluoride

: 591-27-5
m-Hydroxyaniline

: 78748-23-9
3-(4-trifluoromethylphenoxy)aniline

Guidance literature:: With potassium tert-butylate; In dimethyl sulfoxide; at 100 ℃; for 16h; Inert atmosphere;

Reference yield:

: 402-43-7
p-trifluoromethylphenyl bromide

: 78748-23-9
3-(4-trifluoromethylphenoxy)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: N,N,N,N,-tetramethylethylenediamine; copper (I) iodide; potassium-t-butoxide / N,N-dimethyl-formamide / 16 h / 130 °C / Inert atmosphere

2: iron⁽⁰⁾; ammonia hydrochloride / ethanol; water monomer / 2 h / 70 °C

With copper (I) iodide; N,N,N,N,-tetramethylethylenediamine; potassium-t-butoxide; iron⁽⁰⁾; ammonia hydrochloride; In ethanol; water monomer; N,N-dimethyl-formamide;

Reference yield:

: 554-84-7
meta-nitrophenol

: 78748-23-9
3-(4-trifluoromethylphenoxy)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: N,N,N,N,-tetramethylethylenediamine; copper (I) iodide; potassium-t-butoxide / N,N-dimethyl-formamide / 16 h / 130 °C / Inert atmosphere

2: iron⁽⁰⁾; ammonia hydrochloride / ethanol; water monomer / 2 h / 70 °C

With copper (I) iodide; N,N,N,N,-tetramethylethylenediamine; potassium-t-butoxide; iron⁽⁰⁾; ammonia hydrochloride; In ethanol; water monomer; N,N-dimethyl-formamide;