Technology Process of 4,5,7-tri-O-benzyl-3-deoxy-3-fluoro-α-D-gluco-hept-2-ulopyranose
There total 3 articles about 4,5,7-tri-O-benzyl-3-deoxy-3-fluoro-α-D-gluco-hept-2-ulopyranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium osmate(VI) dihydrate; water; potassium carbonate; potassium hexacyanoferrate(III);
In
tert-butyl alcohol;
at 20 ℃;
for 24h;
DOI:10.1055/s-0031-1289598
- Guidance literature:
-
Multi-step reaction with 2 steps
1: toluene / 48 h / 75 °C / Inert atmosphere
2: potassium osmate(VI) dihydrate; water; potassium carbonate; potassium hexacyanoferrate(III) / tert-butyl alcohol / 24 h / 20 °C
With
potassium osmate(VI) dihydrate; water; potassium carbonate; potassium hexacyanoferrate(III);
In
toluene; tert-butyl alcohol;
2: Sharpless dihydroxylation;
DOI:10.1055/s-0031-1289598
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetic anhydride; dimethyl sulfoxide / 24 h / 30 °C
2: toluene / 48 h / 75 °C / Inert atmosphere
3: potassium osmate(VI) dihydrate; water; potassium carbonate; potassium hexacyanoferrate(III) / tert-butyl alcohol / 24 h / 20 °C
With
potassium osmate(VI) dihydrate; water; acetic anhydride; potassium carbonate; dimethyl sulfoxide; potassium hexacyanoferrate(III);
In
toluene; tert-butyl alcohol;
3: Sharpless dihydroxylation;
DOI:10.1055/s-0031-1289598
