3-(Thiophen-3-YL)prop-2-ynenitrile

Base Information

Chemical Name:3-(Thiophen-3-YL)prop-2-ynenitrile
CAS No.:73606-42-5
Molecular Formula:C₇H₃NS
Molecular Weight:133.174
Hs Code.:
DSSTox Substance ID:DTXSID80501828
Nikkaji Number:J3.240.299B
Mol file:73606-42-5.mol

Synonyms:73606-42-5;3-(THIOPHEN-3-YL)PROP-2-YNENITRILE;DTXSID80501828;AKOS026733521

Suppliers and Price of 3-(Thiophen-3-YL)prop-2-ynenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-(Thiophen-3-YL)prop-2-ynenitrile

Chemical Property:

Melting Point:39.5 °C
Boiling Point:227.1±32.0 °C(Predicted)
PSA：52.03000
Density:1.25±0.1 g/cm3(Predicted)
LogP:1.62318
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:132.99862027
Heavy Atom Count:9
Complexity:199

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CSC=C1C#CC#N

Technology Process of 3-(Thiophen-3-YL)prop-2-ynenitrile

There total 5 articles about 3-(Thiophen-3-YL)prop-2-ynenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 67237-53-0
3-ethynylthiophene

: 73789-56-7
N-isocyaniminotriphenylphosphorane

: 73606-42-5
3-(thiophen-3-yl)propiolonitrile

Guidance literature:: With silver trifluoromethanesulfonate; In water; N,N-dimethyl-formamide; at 80 ℃; for 6h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.7b02743

Reference yield: 58.0%

: 67237-53-0
3-ethynylthiophene

: 506-78-5
cyanogen iodide

: 73606-42-5
3-(thiophen-3-yl)propiolonitrile

Guidance literature:: With 2,2,6,6-tetramethyl-piperidine; copper(I) trifluoromethanesulfonate toluene adduct (1/1); In tetrahydrofuran; at 60 ℃; for 17h; Schlenk technique; Inert atmosphere;
DOI:10.1021/ol402863g