(E)-cyclooctyl-4-d brosylate

Base Information

• Chemical Name: (E)-cyclooctyl-4-d brosylate
• CAS No.: 79734-95-5
• Molecular Formula: C₁₄H₁₉BrO₃S
• Molecular Weight: 348.265
• Mol file: 79734-95-5.mol

Synonyms:(E)-cyclooctyl-4-d brosylate

Chemical Property of (E)-cyclooctyl-4-d brosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-cyclooctyl-4-d brosylate

There total 2 articles about (E)-cyclooctyl-4-d brosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

(E)-cyclooctanol-4-d (79734-94-4) + 4-bromobenzenesulfonyl chloride (98-58-8) → (E)-cyclooctyl-4-d brosylate (79734-95-5)

Guidance literature:

In pyridine;

DOI:10.1021/ja00365a036

Reference yield:

cis-1,4-dihydroxycyclooctane (73982-04-4) → (E)-cyclooctyl-4-d brosylate (79734-95-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) p-toluenesulfonyl chloride, 2.) 1.00 N LiEt₃BD / 1.) pyridine, -5 deg C, 24 h, 2.) THF

2: 79 percent / pyridine

With lithium triethyl borodeuteride; p-toluenesulfonyl chloride; In pyridine;

DOI:10.1021/ja00365a036

upstream raw materials:

(E)-cyclooctanol-4-d

4-bromobenzenesulfonyl chloride

cis-1,4-dihydroxycyclooctane