(4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

Base Information

Chemical Name:(4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol
CAS No.:1299474-07-9
Molecular Formula:C₂₀H₁₉FN₂O
Molecular Weight:322.382
Hs Code.:

Synonyms:(4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

Suppliers and Price of (4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

There total 1 articles about (4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1299474-07-9
(4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

Guidance literature:

Reference yield: 88.0%

: 1299474-41-1
ethyl 2-(2-chloro-4-fluoropyridin-3-yl)acetate

: 1299474-07-9
(4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

: 1299474-42-2
ethyl (2-{2-[(4aS,5R)-4a-ethyl-1-(4-fluorophenyl)-5-hydroxy-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethynyl}-4-fluoropyridin-3-yl)acetate

Guidance literature:: With copper(l) iodide; diisopropylamine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; at 90 ℃; for 2h; Inert atmosphere; Sealed;

Reference yield: 84.0%

: 1299474-39-7
(2R)-2-fluoro-2-(2-fluoro-6-iodophenyl)ethanamide

: 1299474-07-9
(4aS,5R)-4a-ethyl-5-ethynyl-1-(4-fluorophenyl)-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-ol

: 1299474-40-0
(2R)-2-(2-{[(4aR,5R)-4a-cyclopropyl-1-(4-fluorophenyl)-5-hydroxy-1,4,4a,5,6,7-hexahydrocyclopenta[f]indazol-5-yl]ethynyl}-6-fluorophenyl)-2-fluoroethanamide

Guidance literature:: With copper(l) iodide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 70 ℃; for 1h; Inert atmosphere; Sealed;