1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol

Base Information

Chemical Name:1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol
CAS No.:1190879-07-2
Molecular Formula:C₁₈H₂₀O₂
Molecular Weight:268.356
Hs Code.:

Synonyms:1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol

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Technology Process of 1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol

There total 1 articles about 1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 151990-53-3
3-methyl-3-phenylcyclobutan-1-one

: 1190879-07-2
1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol

Guidance literature:: 3-methyl-3-phenylcyclobutan-1-one; 4-methoxyphenyl-(Li or MgHal); In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;

With water; ammonium chloride; In tetrahydrofuran;
DOI:10.1002/anie.200903189

Reference yield: 88.0%

: 1190879-07-2
1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol

: 1190879-18-5
(R)-1-(4-methoxyphenyl)-3,3-dimethyl-indanol

Guidance literature:: With [Rh(OH)(cod)]2; (2R)-1-[(1R)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-[bis[4-(trifluoromethyl)phenyl]phosphino]ferrocene; In toluene; at 110 ℃; for 7h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1002/anie.200903189

Reference yield:

: 1190879-07-2
1-(4-methoxyphenyl)-3-methyl-3-phenylcyclobutanol

: C₁₈H₂₀O₂

Guidance literature:: With [Rh(OH)(cod)]2; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In 5,5-dimethyl-1,3-cyclohexadiene; at 23 - 120 ℃; for 12.1667h; Inert atmosphere;
DOI:10.1055/s-0029-1219959