1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam

Base Information

Chemical Name:1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam
CAS No.:244248-97-3
Molecular Formula:C₃₀H₂₇BrN₂O₅S
Molecular Weight:607.525
Hs Code.:

Synonyms:1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam

Suppliers and Price of 1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam

There total 4 articles about 1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1950-69-2
toluene-p-sulfonyl bromide

: 164354-37-4
(+)-(3S,4R)-3-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]-1-propargyl-4-(E)-styryl-2-azetidinone

: 244248-97-3
1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam

Guidance literature:: With 2,2'-azobis(isobutyronitrile); In benzene; Heating;
DOI:10.1021/jo9823994

Reference yield:

: 14371-10-9
(E)-3-phenylpropenal

: 244248-97-3
1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam

Guidance literature:: Multi-step reaction with 3 steps

1: MgSO₄ / CH₂Cl₂ / 20 °C

2: 2.86 g / Et₃N; PhOP(O)Cl₂ / CH₂Cl₂ / 0 - 20 °C

3: 85 percent / AIBN / benzene / Heating

With 2,2'-azobis(isobutyronitrile); magnesium sulfate; O-phenyl phosphorodichloridate; triethylamine; In dichloromethane; benzene; 1: Condensation / 2: Staudinger cyclization / 3: Cyclization;
DOI:10.1021/jo9823994

Reference yield:

: 123882-32-6,136861-61-5,99333-54-7
2-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]acetic acid

: 244248-97-3
1-(α-bromobenzyl)-2-(Z-p-toluenesulfonylmethylene)-6-[(S)-4-phenyl-2-oxo-1,3-oxazolidin-3-yl]carbapenam

Guidance literature:: Multi-step reaction with 2 steps

1: 2.86 g / Et₃N; PhOP(O)Cl₂ / CH₂Cl₂ / 0 - 20 °C

2: 85 percent / AIBN / benzene / Heating

With 2,2'-azobis(isobutyronitrile); O-phenyl phosphorodichloridate; triethylamine; In dichloromethane; benzene; 1: Staudinger cyclization / 2: Cyclization;
DOI:10.1021/jo9823994