Uridine5'-(tetrahydrogen triphosphate), 3'-deoxy- (9CI)

Base Information

Chemical Name:Uridine5'-(tetrahydrogen triphosphate), 3'-deoxy- (9CI)
CAS No.:69199-40-2
Molecular Formula:C₉H₁₅N₂O₁₄P₃
Molecular Weight:468.144
Hs Code.:

Synonyms:3'-DeoxyUTP; 3'-Deoxyuridine-5'-triphosphate

Suppliers and Price of Uridine5'-(tetrahydrogen triphosphate), 3'-deoxy- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
3'-Deoxyuridine-5'-triphosphate
1mg
$ 1600.00

Total 5 raw suppliers

Chemical Property of Uridine5'-(tetrahydrogen triphosphate), 3'-deoxy- (9CI)

Chemical Property:

PSA：273.83000
Density:2.01g/cm3
LogP:-1.05940

Purity/Quality:

97% ^*data from raw suppliers

3'-Deoxyuridine-5'-triphosphate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Uridine5'-(tetrahydrogen triphosphate), 3'-deoxy- (9CI)

There total 13 articles about Uridine5'-(tetrahydrogen triphosphate), 3'-deoxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(6-amino-1-hexynyl)-3'-deoxyuridine-5'-triphosphate: 5-(6-amino-1-hexynyl)-3'-deoxyuridine-5'-triphosphate

FAM-(Pro)8-Lys(εTMR): FAM-(Pro)8-Lys(εTMR)

: 74124-79-1
di(succinimido) carbonate

: 69199-40-2
3'-dUTP

Guidance literature:: With dmap; In water; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 1-O-acetyl-2,5-di-O-p-chlorobenzoyl-3-deoxy-D-ribofuranose

: 69199-40-2
3'-dUTP

Guidance literature:: Multi-step reaction with 6 steps

1: 78 percent / TMS-triflate / acetonitrile / 24 h / Ambient temperature

2: 91.2 percent / hydrazine hydrate / acetic acid; pyridine / Ambient temperature

3: 96 percent / sodium nitrite, fluoroacetic acid / 5 h / 0 °C

4: 65.8 percent / 0.05 N methanolic sodium methoxide / 3 h / 50 °C

5: 78 percent / phosphoryl chloride, triethylphosphate / 12 h / 0 °C

6: 1.) N,N'carbonyldiimidazole, 2.) tri-n-butylammonium pyrophosphate / 1.) DMF, RT, 3.5 h, 2.) DMF, RT, 24 h

With triethyl phosphate; Fluoroacetic acid; trimethylsilyl trifluoromethanesulfonate; sodium methylate; tri(n-butyl)ammonium pyrophosphate; hydrazine hydrate; 1,1'-carbonyldiimidazole; sodium nitrite; trichlorophosphate; In pyridine; acetic acid; acetonitrile;
DOI:10.1248/cpb.43.2005

Reference yield:

: 173601-08-6
2',5'-di-O-p-chlorobenzoyl-N⁴-propionyl-3'-deoxycytidine

: 69199-40-2
3'-dUTP

Guidance literature:: Multi-step reaction with 5 steps

1: 91.2 percent / hydrazine hydrate / acetic acid; pyridine / Ambient temperature

2: 96 percent / sodium nitrite, fluoroacetic acid / 5 h / 0 °C

3: 65.8 percent / 0.05 N methanolic sodium methoxide / 3 h / 50 °C

4: 78 percent / phosphoryl chloride, triethylphosphate / 12 h / 0 °C

5: 1.) N,N'carbonyldiimidazole, 2.) tri-n-butylammonium pyrophosphate / 1.) DMF, RT, 3.5 h, 2.) DMF, RT, 24 h

With triethyl phosphate; Fluoroacetic acid; sodium methylate; tri(n-butyl)ammonium pyrophosphate; hydrazine hydrate; 1,1'-carbonyldiimidazole; sodium nitrite; trichlorophosphate; In pyridine; acetic acid;
DOI:10.1248/cpb.43.2005