(1S,3S,5S)-2-(2-hydroxy-hexanoyl)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide

Base Information

Chemical Name:(1S,3S,5S)-2-(2-hydroxy-hexanoyl)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide
CAS No.:1097133-13-5
Molecular Formula:C₂₀H₂₅ClN₆O₃
Molecular Weight:432.91
Hs Code.:

Synonyms:(1S,3S,5S)-2-(2-hydroxy-hexanoyl)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (1S,3S,5S)-2-(2-hydroxy-hexanoyl)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide

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Technology Process of (1S,3S,5S)-2-(2-hydroxy-hexanoyl)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide

There total 2 articles about (1S,3S,5S)-2-(2-hydroxy-hexanoyl)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1097134-22-9
2-trimethylsilanyloxy-hexanoyl chloride

: 1097263-88-1
(1S,3S,5S)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide

: 1097133-13-5
(1S,3S,5S)-2-(2-hydroxy-hexanoyl)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide

Guidance literature:: 2-trimethylsilanyloxy-hexanoyl chloride; (1S,3S,5S)-2-aza-bicyclo[3.1.0]hexane-3-carboxylic acid 5-chloro-2-tetrazol-1-yl-benzylamide; With pyridine; In dichloromethane; at 20 ℃; for 72h;

With trifluoroacetic acid; In methanol; dichloromethane; for 0.25h;

With sodium hydrogencarbonate; In methanol; dichloromethane; water;