Technology Process of Phenyl-(toluene-4-sulfonyl)-acetaldehyde
There total 5 articles about Phenyl-(toluene-4-sulfonyl)-acetaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron trifluoride diethyl etherate;
In
dichloromethane;
at 0 ℃;
for 0.166667h;
DOI:10.1055/s-1983-30449
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 65 percent / 50percent aq. NaOH / benzyltriethylammonium chloride / acetonitrile / 1 h / Ambient temperature
2: boron trifluoride-etherate / CH2Cl2 / 0.17 h / 0 °C
With
sodium hydroxide; boron trifluoride diethyl etherate;
N-benzyl-N,N,N-triethylammonium chloride;
In
dichloromethane; acetonitrile;
DOI:10.1055/s-1983-30449
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dichloromethane / 1.5 h / -30 - 20 °C
1.2: 3.5 h / 20 °C / Darkness
2.1: methanol / 0.75 h / 0 - 20 °C / Inert atmosphere
3.1: water / dimethyl sulfoxide / 16 h / 20 °C
With
water;
In
methanol; dichloromethane; dimethyl sulfoxide;
DOI:10.3390/molecules21081073
