(2S,3R)-dimethyl 2-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methyl)-3-hydroxysuccinate

Base Information

Chemical Name:(2S,3R)-dimethyl 2-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methyl)-3-hydroxysuccinate
CAS No.:1196672-33-9
Molecular Formula:C₁₉H₂₄N₂O₅
Molecular Weight:360.41
Hs Code.:

Synonyms:(2S,3R)-dimethyl 2-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methyl)-3-hydroxysuccinate

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Chemical Property of (2S,3R)-dimethyl 2-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methyl)-3-hydroxysuccinate

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Technology Process of (2S,3R)-dimethyl 2-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methyl)-3-hydroxysuccinate

There total 1 articles about (2S,3R)-dimethyl 2-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methyl)-3-hydroxysuccinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 70681-41-3
(R)-dimethyl malate

: 1196672-22-6
2-(bromomethyl)-6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridine

: 1196672-33-9
(2S,3R)-dimethyl 2-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methyl)-3-hydroxysuccinate

: (2R,3R)-dimethyl 2-((6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridin-2-yl)methyl)-3-hydroxysuccinate

Guidance literature:: (R)-dimethyl malate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - 0 ℃; Inert atmosphere;

2-(bromomethyl)-6-(2,5-dimethyl-1H-pyrrol-1-yl)-4-methylpyridine; In tetrahydrofuran; at -78 - 20 ℃; optical yield given as %de; Inert atmosphere;
DOI:10.1021/ol902109t