methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate

Base Information

Chemical Name:methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate
CAS No.:1263103-46-3
Molecular Formula:C₂₃H₂₃N₃O₇
Molecular Weight:453.452
Hs Code.:

Synonyms:methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate

Suppliers and Price of methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate

There total 3 articles about methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 446292-07-5
2-((2S)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione

: 79-22-1
methyl chloroformate

: 1263103-46-3
methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate

Guidance literature:: 2-((2S)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione; methyl chloroformate; With N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 4.05h;

In acetonitrile;

Reference yield:

: 438056-69-0
4-(4-aminophenyl)morpholin-3-one

: 1263103-46-3
methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: isopropyl alcohol / 14 h / 20 °C / Reflux

2: N,N-dimethyl-formamide / 3 h / 20 - 100 °C

3: N-ethyl-N,N-diisopropylamine / acetonitrile / 4.05 h / 20 °C

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; isopropyl alcohol; acetonitrile;

Reference yield:

: 1252018-10-2
4-[4-(N-(3-chloro-(2R)-2-hydroxy-1-propyl)amino)phenyl]morpholin-3-one

: 1263103-46-3
methyl (S)-2-hydroxy-3-(1,3-dioxoisoindolin-2-yl)propyl-4-(3oxomorpholino)phenylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 3 h / 20 - 100 °C

2: N-ethyl-N,N-diisopropylamine / acetonitrile / 4.05 h / 20 °C

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; acetonitrile;