Technology Process of C21H14F5NO3
There total 11 articles about C21H14F5NO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
water; sodium hydroxide;
In
tetrahydrofuran;
at 20 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C
2.1: tetrahydrofuran / 3.17 h / 0 - 20 °C
3.1: borane-THF / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere; Reflux
4.1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C
4.2: 1 h / 20 °C
5.1: water; sodium hydroxide / tetrahydrofuran / 3 h / 20 °C
With
borane-THF; oxalyl dichloride; water; caesium carbonate; N,N-dimethyl-formamide; sodium hydroxide;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; methanol / 80 °C / Inert atmosphere
2.1: water; sodium hydroxide / tetrahydrofuran; methanol / 3 h / 20 °C / Reflux
3.1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C
4.1: tetrahydrofuran / 3.17 h / 0 - 20 °C
5.1: borane-THF / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere; Reflux
6.1: caesium carbonate / N,N-dimethyl-formamide / 1 h / 20 °C
6.2: 1 h / 20 °C
7.1: water; sodium hydroxide / tetrahydrofuran / 3 h / 20 °C
With
tetrakis(triphenylphosphine) palladium(0); borane-THF; oxalyl dichloride; water; potassium carbonate; caesium carbonate; N,N-dimethyl-formamide; sodium hydroxide;
In
tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide;
