1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide

Base Information

• Chemical Name: 1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide
• CAS No.: 921590-98-9
• Molecular Formula: C₂₃H₁₈Cl₂N₄O₂
• Molecular Weight: 453.328

Synonyms:1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide

Chemical Property of 1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide

There total 1 articles about 1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

5-[4-(benzyloxy)phenyl]-1-(2,4-dichlorophenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide (921590-97-8) → 1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide (921590-98-9)

Guidance literature:

5-[4-(benzyloxy)phenyl]-1-(2,4-dichlorophenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide; With hydrogen bromide; acetic acid; at 20 ℃; for 4h;

With sodium carbonate; pH=~ 7;

Reference yield: 70.0%

1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide (921590-98-9) + isoamylsulfonyl chloride (22795-37-5) → 4-(1-(2,4-dichlorophenyl)-4-methyl-3-{[(5-methylpyridin-2-yl)amino]carbonyl}-1H-pyrazol-5-yl)phenyl 3-methylbutane-1-sulfonate

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

Reference yield: 65.0%

1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide (921590-98-9) + 3,3,3-trifluoropropane-1-sulfonyl chloride (845866-80-0) → 3,3,3-trifluoro-propane-1-sulfonic acid 4-[2-(2,4-dichlorophenyl)-4-methyl-5-(5-methyl-pyridin-2-ylcarbamoyl)-2H-pyrazol-3-yl]phenyl ester

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

upstream raw materials:

5-[4-(benzyloxy)phenyl]-1-(2,4-dichlorophenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 921590-98-9 1-(2,4-dichlorophenyl)-5-(4-hydroxyphenyl)-4-methyl-N-(5-methylpyridin-2-yl)-1H-pyrazole-3-carboxamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send