(E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone

Base Information

Chemical Name:(E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone
CAS No.:878277-38-4
Molecular Formula:C₂₅H₃₀O₅
Molecular Weight:410.51
Hs Code.:

Synonyms:(E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone

Suppliers and Price of (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone

There total 7 articles about (E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1528767-73-8
(E)-1-{(3″S)-[3″-(tert-butyldimethylsilanyloxy)-3″,7″-dimethyloct-6″-enyl]-2′,4′-dihydroxyphenyl}-3-(4-hydroxyphenyl)propenone

: 878277-38-4
(E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 80 ℃; for 8h; Molecular sieve;
DOI:10.1016/j.tet.2013.11.106

Reference yield:

: 888481-17-2
(3S)-3-((tert-butyldimethylsilanyl)oxy)-3,7-dimethyloct-6-en-1-ol

: 878277-38-4
(E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone

Guidance literature:: Multi-step reaction with 4 steps

1.1: carbon tetrabromide / dichloromethane / 0.17 h / 20 °C / Inert atmosphere

1.2: 0 °C / Inert atmosphere

2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 20 h / 20 °C

3.1: silica gel supported KHSO₄ / 0.08 h / 72 °C / 3900.39 - 4050.41 Torr / Microwave irradiation

4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 8 h / 80 °C / Molecular sieve

With carbon tetrabromide; tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; dichloromethane; 3.1: |Claisen-Schmidt Condensation;
DOI:10.1016/j.tet.2013.11.106

Reference yield:

: 1528767-71-6
(1S)[1-(2′-bromoethyl)-1,5-dimethylhex-4-enyloxy]tert-butyldimethylsilane

: 878277-38-4
(E)-1-[2′,4′-dihydroxy-(3″S)-(3″-hydroxy-3″,7″-dimethyloct-6″-enyl)phenyl]-3-(4-hydroxyphenyl)propenone

Guidance literature:: Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 20 h / 20 °C

2: silica gel supported KHSO₄ / 0.08 h / 72 °C / 3900.39 - 4050.41 Torr / Microwave irradiation

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 8 h / 80 °C / Molecular sieve

With tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; 2: |Claisen-Schmidt Condensation;
DOI:10.1016/j.tet.2013.11.106