5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole

Base Information

Chemical Name:5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole
CAS No.:1132701-03-1
Molecular Formula:C₁₈H₁₁BrClF₆NO
Molecular Weight:486.639
Hs Code.:

Synonyms:5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole

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Technology Process of 5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole

There total 1 articles about 5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1132701-02-0
3-[3-bromo-5-(trifluoromethyl) phenyl]-1-(3-chloro-4-methylphenyl)-4,4,4-trifluoro-2-butene-1-one

: 1132701-03-1
5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole

Guidance literature:: With tetrabutylammomium bromide; hydroxylamine sulfate; sodium hydroxide; In water; toluene; at 20 ℃; Cooling with ice;

Reference yield:

: 1132701-03-1
5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole

: 1074-82-4
potassium phtalimide

: 1132701-04-2
N-[[4-[5-[3-bromo-5-(trifluoromethyl) phenyl]-5-trifluoromethyl-4,5-dihydroisoxazole-3-yl]-2-chlorophenyl] methyl] phthalimide

Guidance literature:: 5-[3-bromo-5-(trifluoromethyl) phenyl]-3-(3-chloro-4-methylphenyl)-5-trifluoromethyl-4,5-dihydroisoxazole; With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In 1,2-dichloro-ethane; for 3h; Reflux;

potassium phtalimide; In N,N-dimethyl-formamide; at 20 ℃; for 1h;