L-Phenylalanine,N-acetyl-L-methionyl-L-leucyl-(9CI)

Base Information

Chemical Name:L-Phenylalanine,N-acetyl-L-methionyl-L-leucyl-(9CI)
CAS No.:73572-34-6
Molecular Formula:C₂₂H₃₃N₃O₅S
Molecular Weight:451.587
Hs Code.:
DSSTox Substance ID:DTXSID80703623
Mol file:73572-34-6.mol

Synonyms:73572-34-6;L-Phenylalanine,N-acetyl-L-methionyl-L-leucyl-(9CI);L-Phenylalanine,N-acetyl-L-methionyl-L-leucyl- (9CI);(2S)-2-acetamido-4-methylsulfanylbutanoic acid;(2S)-2-amino-4-methylpentanoic acid;(2S)-2-amino-3-phenylpropanoic acid;DTXSID80703623

Suppliers and Price of L-Phenylalanine,N-acetyl-L-methionyl-L-leucyl-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of L-Phenylalanine,N-acetyl-L-methionyl-L-leucyl-(9CI)

Chemical Property:

Boiling Point:786.9±60.0 °C(Predicted)
PKA:3.50±0.10(Predicted)
PSA：221.83000
Density:1.184±0.06 g/cm3(Predicted)
LogP:3.65510
Storage Temp.:−20°C
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:11
Exact Mass:487.23522170
Heavy Atom Count:33
Complexity:426

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)O)N.CC(=O)NC(CCSC)C(=O)O.C1=CC=C(C=C1)CC(C(=O)O)N
Isomeric SMILES:CC(C)C[C@@H](C(=O)O)N.CC(=O)N[C@@H](CCSC)C(=O)O.C1=CC=C(C=C1)C[C@@H](C(=O)O)N

Technology Process of L-Phenylalanine,N-acetyl-L-methionyl-L-leucyl-(9CI)

There total 1 articles about L-Phenylalanine,N-acetyl-L-methionyl-L-leucyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-24-7
acetic anhydride

: 67247-12-5
tert-butyloxycarbonyl-methionyl-leucyl-phenylalanine

: 73572-34-6
formyl-methionyl-leucyl-phenylalanine

Guidance literature:: tert-butyloxycarbonyl-methionyl-leucyl-phenylalanine; With trifluoroacetic acid; In dichloromethane; for 0.5h;

acetic anhydride; With 4-methyl-morpholine; for 0.5h;

Reference yield:

: beta-alanine methyl ester hydrochloride

: 73572-34-6
formyl-methionyl-leucyl-phenylalanine

: α-MLF-β-Ala-OH

Guidance literature:: beta-alanine methyl ester hydrochloride; formyl-methionyl-leucyl-phenylalanine; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; for 0.25h;

With sodium hydroxide; In water; for 0.5h;

Reference yield:

: 73572-34-6
formyl-methionyl-leucyl-phenylalanine

: Ac-MLF-β-ala-OSu

Guidance literature:: Multi-step reaction with 2 steps

1.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.25 h

1.2: 0.5 h

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.92 h

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide;