5-methyl-2-nitro-3-phenyl-benzofuran

Base Information

• Chemical Name: 5-methyl-2-nitro-3-phenyl-benzofuran
• CAS No.: 70048-36-1
• Molecular Formula: C₁₅H₁₁NO₃
• Molecular Weight: 253.257
• Mol file: 70048-36-1.mol

Synonyms:5-methyl-2-nitro-3-phenyl-benzofuran

Chemical Property of 5-methyl-2-nitro-3-phenyl-benzofuran

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-methyl-2-nitro-3-phenyl-benzofuran

There total 4 articles about 5-methyl-2-nitro-3-phenyl-benzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2,5,6-tetrahydrobenzoic acid (4771-80-6) + 2-bromo-5-methyl-3-phenyl-benzofuran (70048-35-0) → 5-methyl-2-nitro-3-phenyl-benzofuran (70048-36-1)

Guidance literature:

With nitric acid; sodium nitrite; In acetic acid;

Reference yield:

5-methyl-3-phenyl-2,3-benzofuran (14385-52-5) → 5-methyl-2-nitro-3-phenyl-benzofuran (70048-36-1)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine / diethyl ether; chloroform; Petroleum ether

2: nitric acid; sodium nitrite / acetic acid

With bromine; nitric acid; sodium nitrite; In diethyl ether; chloroform; acetic acid; Petroleum ether;

Reference yield:

2-(4-methylphenoxy)acetophenone (14538-45-5) → 5-methyl-2-nitro-3-phenyl-benzofuran (70048-36-1)

Guidance literature:

Multi-step reaction with 3 steps

1: PPA

2: bromine / diethyl ether; chloroform; Petroleum ether

3: nitric acid; sodium nitrite / acetic acid

With PPA; bromine; nitric acid; sodium nitrite; In diethyl ether; chloroform; acetic acid; Petroleum ether;

upstream raw materials:

1,2,5,6-tetrahydrobenzoic acid

2-bromo-5-methyl-3-phenyl-benzofuran

5-methyl-3-phenyl-2,3-benzofuran

2-(4-methylphenoxy)acetophenone

Refernces