3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride

Base Information

• Chemical Name: 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride
• CAS No.: 365462-49-3
• Molecular Formula: C₂₈H₃₀N₄O₅*ClH
• Molecular Weight: 539.031
• Mol file: 365462-49-3.mol

Synonyms:3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride

Chemical Property of 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride

There total 5 articles about 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride (365462-45-9) → 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride (365462-49-3)

Guidance literature:

ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride; With sodium hydroxide; In methanol; water; at 20 ℃; for 4h;

With hydrogenchloride; In water;

DOI:10.1021/jm200868m

Reference yield:

C30H34N4O5 (765891-23-4) → 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride (365462-49-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / water

2: sodium hydroxide / methanol; water / 4 h / 20 °C

With hydrogenchloride; sodium hydroxide; In methanol; water;

DOI:10.1021/jm200868m

Reference yield:

ethyl 2-amino-3-[(4-methoxybenzoyl)amino]benzoate (1350454-17-9) → 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoic acid hydrochloride (365462-49-3)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / 19 h / 20 °C

2: hydrogenchloride / water

3: sodium hydroxide / methanol; water / 4 h / 20 °C

With pyridine; hydrogenchloride; sodium hydroxide; In methanol; water;

DOI:10.1021/jm200868m

upstream raw materials:

C₃₀H₃₄N₄O₅

ethyl 2-amino-3-[(4-methoxybenzoyl)amino]benzoate

ethyl 3-[(4-methoxybenzoyl)amino]-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzoate hydrochloride

2,3-Diaminobenzoic acid,ethyl ester