N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile

Base Information

• Chemical Name: N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile
• CAS No.: 101195-43-1
• Molecular Formula: C₁₃H₁₂ClN₃
• Molecular Weight: 245.711
• Mol file: 101195-43-1.mol

Synonyms:N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile

Chemical Property of N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile

There total 1 articles about N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.0%

4-bromobut-2-enenitrile (42879-03-8) + N-(β-cyanoethyl)-o-chloroaniline (94-89-3) → N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile (101195-43-1) + N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile (101195-42-0)

Guidance literature:

With sodium carbonate; In ethanol; water; for 52h; Heating;

Reference yield: 4.4%

N-(β-cyanoethyl)-N-(o-chlorophenyl)-4-amino-2-butenenitrile (101195-43-1) → N-(β-cyanoethyl)-o-chloroaniline (94-89-3) + 1-methyl-2,3-dihydroindole-3-acetonitrile (101195-49-7)

Guidance literature:

With triethylaluminum; pyridine; bis(acetylacetonate)nickel(II); In tetrahydrofuran; toluene; at 80 - 100 ℃; for 5h;

upstream raw materials:

4-bromobut-2-enenitrile

N-(β-cyanoethyl)-o-chloroaniline

Downstream raw materials:

N-(β-cyanoethyl)-o-chloroaniline

1-methyl-2,3-dihydroindole-3-acetonitrile