{2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid

Base Information

• Chemical Name: {2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid
• CAS No.: 1224967-53-6
• Molecular Formula: C₂₃H₂₆N₂O₆
• Molecular Weight: 426.469
• Mol file: 1224967-53-6.mol

Synonyms:{2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid

Chemical Property of {2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid

Chemical Property:

Purity/Quality:

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Technology Process of {2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid

There total 1 articles about {2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C23H24N2O5 → {2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid (1224967-53-6)

Guidance literature:

C₂₃H₂₄N₂O₅; With water; potassium carbonate; at 100 ℃; for 1h; Inert atmosphere;

With hydrogenchloride; In water; at 0 ℃; Inert atmosphere;

DOI:10.1021/jo1003339

Reference yield: 87.0%

{2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid (1224967-53-6) → 3-[(benzyl-tert-butoxycarbonyl-amino)-methyl]-2-oxo-1,2-dihydro-quinoline-4-carboxylic acid (1224967-67-2)

Guidance literature:

{2-[3-(benzyl-tert-butoxycarbonyl-amino)-propionylamino]-phenyl}-oxo-acetic acid; With potassium tert-butylate; In N,N-dimethyl-formamide; at 80 ℃; for 4h; Inert atmosphere;

With hydrogenchloride; In water; N,N-dimethyl-formamide; at 0 ℃; pH=3; Inert atmosphere;

DOI:10.1021/jo1003339

Downstream raw materials:

3-[(benzyl-tert-butoxycarbonyl-amino)-methyl]-2-oxo-1,2-dihydro-quinoline-4-carboxylic acid