Technology Process of (2E)-3-(2-allylphenyl)prop-2-en-1-ol
There total 3 articles about (2E)-3-(2-allylphenyl)prop-2-en-1-ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
ethyl (2E)-3-(2-allylphenyl)prop-2-enoate;
With
diisobutylaluminium hydride;
In
diethyl ether;
at -78 - 20 ℃;
for 3h;
With
methanol; rochelle salt;
In
diethyl ether;
at 0 ℃;
for 1h;
DOI:10.1021/jo100995k
- Guidance literature:
-
Multi-step reaction with 2 steps
1: cesium fluoride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 18 h / 85 °C
2: diisobutylaluminium hydride / hexane; diethyl ether / 18 h / -78 - 20 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; diisobutylaluminium hydride; cesium fluoride;
In
1,4-dioxane; diethyl ether; hexane;
1: |Suzuki-Miyaura Coupling;
DOI:10.1021/jo5014492
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium bromide; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 0.5 h / 20 °C / Inert atmosphere
1.2: 18 h / 20 °C / Inert atmosphere
2.1: cesium fluoride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane / 18 h / 85 °C
3.1: diisobutylaluminium hydride / hexane; diethyl ether / 18 h / -78 - 20 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; diisobutylaluminium hydride; 1,8-diazabicyclo[5.4.0]undec-7-ene; cesium fluoride; lithium bromide;
In
1,4-dioxane; diethyl ether; hexane; acetonitrile;
2.1: |Suzuki-Miyaura Coupling;
DOI:10.1021/jo5014492
