6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE

Base Information

Chemical Name:6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE
CAS No.:78238-94-5
Molecular Formula:C18H20 O2
Molecular Weight:268.356
Hs Code.:2909309090
Mol file:78238-94-5.mol

Synonyms:6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE;6,7-Dimethoxy-4-phenyl 1,2,3,4-tetrahydroisoquinoline hydrochloride

Suppliers and Price of 6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE 95.00%
500MG
$ 2728.69

American Custom Chemicals Corporation
6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE 95.00%
100MG
$ 1091.48

Total 3 raw suppliers

Chemical Property of 6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE

Chemical Property:

Vapor Pressure:6.28E-08mmHg at 25°C
Boiling Point:433.7°C at 760 mmHg
Flash Point:216.1°C
PSA：30.49000
Density:1.080±0.06 g/cm3(Predicted)
LogP:4.06970

Purity/Quality:

99% ^*data from raw suppliers

6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE

There total 10 articles about 6,7-DIMETHOXY-4-PHENYL 1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHOLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 221158-41-4
4-(3,4-dimethoxyphenyl)-1-phenylbutan-1-one

: 78238-94-5
6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene

Guidance literature:: With triethylsilane; trifluoroacetic acid; at 20 ℃; for 2.5h;
DOI:10.1016/j.bmcl.2007.04.092

Reference yield: 80.0%

: 78238-92-3
6,7-dimethoxy-1-phenyl-3,4-dihydronaphthalene

: 78238-94-5
6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethanol; for 8h; under 2660 Torr;

Reference yield:

: 13575-74-1
4-(3,4-dimethoxyphenyl)butanoic acid

: 78238-94-5
6,7-dimethoxy-1-phenyl-1,2,3,4-tetrahydronaphthalene

Guidance literature:: Multi-step reaction with 5 steps

1: 89 percent / lithium aluminum hydride / tetrahydrofuran / 3.5 h / 20 °C

2: 77 percent / pyridinium chlorochromate / CH₂Cl₂ / 1 h / 20 °C

3: 66 percent / tetrahydrofuran / -78 - 20 °C

4: 65 percent / pyridinium chlorochromate / CH₂Cl₂ / 1 h / 20 °C

5: 90 percent / TFA; Et₃SiH / 2.5 h / 20 °C

With triethylsilane; lithium aluminium tetrahydride; pyridinium chlorochromate; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmcl.2007.04.092