(S)-(+)-2-Hexanol

Base Information

• Chemical Name: (S)-(+)-2-Hexanol
• CAS No.: 52019-78-0
• Molecular Formula: C6H14O
• Molecular Weight: 102.177
• Hs Code.: 2905199090
• Mol file: 52019-78-0.mol

Synonyms:(+)-2-Hexanol;(2S)-Hexan-2-ol;(S)-2-Hexanol;

Chemical Property of (S)-(+)-2-Hexanol

Chemical Property:

• Appearance/Colour: Colorless to light yellow liquid
• Vapor Pressure: 2.63mmHg at 25°C
• Melting Point: -48.42°C (estimate)
• Refractive Index: n20/D 1.415(lit.)
• Boiling Point: 139.7 °C at 760 mmHg
• PKA: 15.31±0.20(Predicted)
• Flash Point: 46.111 °C
• PSA: 20.23000
• Density: 0.814 g/cm³
• LogP: 1.55740
• Storage Temp.: Flammables area
• Water Solubility.: Slightly soluble in water

Purity/Quality:

97% ^*data from raw suppliers

(S)-(+)-2-Hexanol 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi,F
• Hazard Codes: Xn,Xi,F,N
• Statements: 10-22-36/37/38-36-51/53
• Safety Statements: 16-26-36-39-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: S)-(+)-2-Hexanol is the S enantiomer used in the preparation of key intermediates for model studies in the total synthesis of antivirally active glycolipid cycloviracin B1.

Technology Process of (S)-(+)-2-Hexanol

There total 12 articles about (S)-(+)-2-Hexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

n-hexan-2-ol (626-93-7) → (+)-2-hexanol (626-93-7,20281-86-1,26549-24-6,52019-78-0) + (-)-hexanol-2 (626-93-7,20281-86-1,26549-24-6,52019-78-0)

Guidance literature:

n-hexan-2-ol; With (R,R,R,R)-(-)-trans,trans-2,3,10,11-tetrakis(hydroxydiphe..; at 20 ℃; for 24h;

at 180 ℃; under 30 Torr;

DOI:10.1002/1099-0690(200009)2000:18<3171::AID-EJOC3171>3.0.CO;2-T

Reference yield: 34.0%

n-hexan-2-ol (626-93-7) → (+)-2-hexanol (626-93-7,20281-86-1,26549-24-6,52019-78-0) + (-)-hexanol-2 (626-93-7,20281-86-1,26549-24-6,52019-78-0)

Guidance literature:

n-hexan-2-ol; With (R,R,R,R)-(-)-trans,trans-2,3,10,11-tetrakis(hydroxydiphe..; at 20 ℃; for 24h;

at 180 ℃; under 30 Torr;

DOI:10.1002/1099-0690(200009)2000:18<3171::AID-EJOC3171>3.0.CO;2-T

Reference yield: 16.0%

n-hexan-2-ol (626-93-7) → (S)-2-hexanol (52019-78-0) + (2R)-hexan-2-ol (26549-24-6) + n-hexan-2-one (591-78-6) + (R)‐2‐aminohexane (5329-79-3,68107-05-1,70095-40-8,70492-67-0)

Guidance literature:

With ammonium hydroxide; D-glucose; ammonium chloride; In water; at 30 ℃; for 24h; pH=8.7; Reagent/catalyst; enantioselective reaction; Microbiological reaction; Green chemistry;

DOI:10.1039/c9gc01059a

upstream raw materials:

(R)-2-Methylpentylamin

n-hexan-2-one

isopropyl alcohol

1-hexene

Downstream raw materials:

2-iodohexane

(-)-O-2-hexyl-N,N'-dicyclohexylisourea

2-hexyl-4'-nitrobenzoate

(2S)-2-hexyl-4'-methylbenzenesulfonate