4-(1H-1,2,3-benzotriazol-1-yl)-5-[(3,4'-dimethyl[1,1'-biphenyl]-4-yl)oxy]phthalonitrile

Base Information

• Chemical Name: 4-(1H-1,2,3-benzotriazol-1-yl)-5-[(3,4'-dimethyl[1,1'-biphenyl]-4-yl)oxy]phthalonitrile
• CAS No.: 448914-27-0
• Molecular Formula: C₂₈H₁₉N₅O
• Molecular Weight: 441.492
• Mol file: 448914-27-0.mol

Synonyms:4-(1-benzotriazolyl)-5-{[3,4'-dimethyl(1,1'-biphenyl)-4-yl]oxy}phthalonitrile

Chemical Property of 4-(1H-1,2,3-benzotriazol-1-yl)-5-[(3,4'-dimethyl[1,1'-biphenyl]-4-yl)oxy]phthalonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(1H-1,2,3-benzotriazol-1-yl)-5-[(3,4'-dimethyl[1,1'-biphenyl]-4-yl)oxy]phthalonitrile

There total 2 articles about 4-(1H-1,2,3-benzotriazol-1-yl)-5-[(3,4'-dimethyl[1,1'-biphenyl]-4-yl)oxy]phthalonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3,4'-dimethyl-(1,1'-biphenyl)-4-ol (175136-31-9) + 4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile (274924-71-9) → 4-(1-benzotriazolyl)-5-{[3,4'-dimethyl(1,1'-biphenyl)-4-yl]oxy}phthalonitrile (448914-27-0)

Guidance literature:

With potassium carbonate; In water; N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1134/S1070363214040185

Reference yield:

4-[(2-aminophenyl)amino]-5-nitro-phthalodinitrile (274924-60-6) → 4-(1-benzotriazolyl)-5-{[3,4'-dimethyl(1,1'-biphenyl)-4-yl]oxy}phthalonitrile (448914-27-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium nitrite; acetic acid

2: potassium carbonate / N,N-dimethyl-formamide; water / 1 h / 20 °C

With potassium nitrite; potassium carbonate; acetic acid; In water; N,N-dimethyl-formamide;

DOI:10.1134/S1070363214040185

Reference yield: 79.0%

4-(1-benzotriazolyl)-5-{[3,4'-dimethyl(1,1'-biphenyl)-4-yl]oxy}phthalonitrile (448914-27-0) → C112H78N20O4 (1610359-71-1)

Guidance literature:

With urea; at 185 ℃; for 2h;

DOI:10.1134/S1070363214040185

upstream raw materials:

3,4'-dimethyl-(1,1'-biphenyl)-4-ol

4-(1H-1,2,3-benzotriazol-1-yl)-5-nitrophthalonitrile

4-[(2-aminophenyl)amino]-5-nitro-phthalodinitrile

Downstream raw materials:

C₁₁₂H₇₈N₂₀O₄