Cyclopropanecarboxaldehyde, 2-(3-oxobutyl)-, (1R,2S)- (9CI)

Base Information

• Chemical Name: Cyclopropanecarboxaldehyde, 2-(3-oxobutyl)-, (1R,2S)- (9CI)
• CAS No.: 32543-79-6
• Molecular Formula: C10 H16 O2
• Molecular Weight: 168.236
• Mol file: 32543-79-6.mol

Synonyms:Cyclopropanecarboxaldehyde, 2,2-dimethyl-3-(3-oxobutyl)-, (1S-cis)-;

Chemical Property of Cyclopropanecarboxaldehyde, 2-(3-oxobutyl)-, (1R,2S)- (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopropanecarboxaldehyde, 2-(3-oxobutyl)-, (1R,2S)- (9CI)

There total 4 articles about Cyclopropanecarboxaldehyde, 2-(3-oxobutyl)-, (1R,2S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(1S,2S,3R,6R)-3,7,7-trimethylbicyclo[4.1.0]heptane-2,3-diol → (1S,3R)-2,2-dimethyl-3-(3-oxobutyl)cyclopropane-1-carbaldehyde (32543-79-6)

Guidance literature:

With sodium periodate; silica gel; In dichloromethane; at 25 ℃;

DOI:10.1002/anie.201100375

Reference yield:

2-carene (4497-92-1) → (1S,3R)-2,2-dimethyl-3-(3-oxobutyl)cyclopropane-1-carbaldehyde (32543-79-6)

Guidance literature:

Multistep reaction; (i) O₃, AcOH, (ii) Zn, Et₂O;

DOI:10.1039/j39710002127

Reference yield:

C10H18O2 → (1S,3R)-2,2-dimethyl-3-(3-oxobutyl)cyclopropane-1-carbaldehyde (32543-79-6)

Guidance literature:

With [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃; for 0.25h;

DOI:10.1039/c7ob01400g

upstream raw materials:

2-carene

Downstream raw materials:

[1aR-(1aα,7α,7aβ,7bα)]-1a,2,3,5,6,7,7a,7b-octahydro-1,1,4,7-tetramethyl-1H-cycloprop[e]azulene

spathulenol

psiguadial A

(1S,3R)-cis-2,2-dimethyl-3-(3-oxobutyl)cyclopropanecarboxylic acid