1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane

Base Information

• Chemical Name: 1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane
• CAS No.: 299411-86-2
• Molecular Formula: C₄₂H₅₄O₁₅S₂
• Molecular Weight: 863.014
• Mol file: 299411-86-2.mol

Synonyms:1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane

Chemical Property of 1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane

There total 2 articles about 1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

p-toluenesulfonyl chloride (98-59-9) + 1,11-bis<4-<2-(2-hydroxyethoxy)ethoxy>phenoxy>-3,6,9-trioxaundecane (142879-03-6) → 1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane (299411-86-2)

Guidance literature:

With triethylamine; In chloroform; at 20 ℃; for 48h;

DOI:10.1021/jo000196l

Reference yield:

1,11-bis<4-hydroxyphenoxy>-3,6,9-trioxaundecane (14556-10-6) → 1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane (299411-86-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / K₂CO₃; KI / acetonitrile / 168 h / Heating

2: 82 percent / Et₃N / CHCl₃ / 48 h / 20 °C

With potassium carbonate; triethylamine; potassium iodide; In chloroform; acetonitrile; 1: Alkylation / 2: Tosylation;

DOI:10.1021/jo000196l

Reference yield: 83.0%

salicylaldehyde (90-02-8) + 1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane (299411-86-2) → 1,11-bis{4-[2-(2-(o-formylphenoxy)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane (652987-61-6)

Guidance literature:

salicylaldehyde; With potassium carbonate; In acetonitrile; for 1h; Heating;

1,11-bis{4-[2-(2-(toluene-p-sulfonyl)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane; In acetonitrile; for 96h; Further stages.; Heating;

DOI:10.1039/b308157e

upstream raw materials:

p-toluenesulfonyl chloride

1,11-bis<4-<2-(2-hydroxyethoxy)ethoxy>phenoxy>-3,6,9-trioxaundecane

1,11-bis<4-hydroxyphenoxy>-3,6,9-trioxaundecane

Downstream raw materials:

1,11-bis{4-[2-(2-(o-formylphenoxy)ethoxy)ethoxy]phenoxy}-3,6,9-trioxaundecane